PUBLICATIONS & DATA
Genomic and proteomic data can be accessed by following the links provided in the Data column on this page or through the Katze Lab Informatics Server.
For questions about or assistance with data access, please contact: help@pandemicinfluenza.org.
| Authors | Title | Citation | Data |
| 2009 | |||
| Baskin, C.R., H. Bielefeldt-Ohmann, T.M. Tumpey, P.J. Sabourin, J.P. Long, A. García-Sastre, A.-E. Tolnay, R. Albrecht, J.A. Pyles, P. Olson, L.D. Aicher, E.R. Rosenzweig, M.K. Kaja, E.E. Clark, M.S. Kotur, J.L. Fornek, S. Proll, R.E. Palermo, C.L. Sabourin, and M.G. Katze | Early and sustained innate immune response defines pathology and death in highly pathogenic influenza-infected nonhuman primates | Proc. Natl. Acad. Sci. USA 106:3455-3460 | |
| Billharz, R., H. Zeng, S.C. Proll, M.J. Korth, S. Lederer, R. Albrecht, A.G. Goodman, E. Rosenzweig, T.M. Tumpey, A. Garcia-Sastre, and M.G. Katze | The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways | J. Virol. 83:10557-10570 | |
| Fornek, J.L., L. Gillim-Ross, C. Santos, V. Carter, J.M. Ward, L.I. Cheng, S. Proll, M.G. Katze, and K. Subbarao | A single amino acid substitution in a polymerase protein of an H5N1 influenza virus is associated with systemic infection and impaired T cell activation in mice | J. Virol. 83:11102-11115 | |
| Peng, X., E.C. Chan, Y. Li, D.L. Diamond, M.J. Korth, and M.G. Katze | Virus-host interactions: from systems biology to translational research | Curr. Op. Microbiol. 12:432-438 | |
| Tisoncik, J.R., S.E. Belisle, D.L. Diamond, M.J. Korth, and M.G. Katze | Is systems biology the key to preventing the next pandemic? | Future Virol. In press. | |
| 2008 TOP | |||
| Basler, C.F and P.V. Aguilar | Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses | Antiviral Res. 79:166-178 | Dittmann, J., S. Stertz, D. Grimm, J. Steel, A. Garcia-Sastre, O. Haller, and G. Kochs | Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase | J. Virol. 82-3624-3631 |
| Katze, M.G., J.L. Fornek, R.E. Palermo, K.-A. Walters, and M.J. Korth | Innate immune modulation by RNA viruses: emerging insights from functional genomics | Nat. Rev. Immunol. 8:644-654 | |
| Loo, Y.M., J. Fornek, N. Crochet, G. Bajwa, O. Perwitasari, L. Martinez-Sobrido, S. Akira, M.A. Gill, A. Garcia-Sastre, M.G. Katze, and M. Gale, Jr. | Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity | J. Virol. 82-335-345 | |
| Mubaeka, S. and P. Palese | The biology of a changing virus | p. 9-30. In R. Rappuoli and G. Del Giudice (ed), Influenza vaccines for the future | |
| Pappas, C., P.V. Aguilar, C.F. Basler, A. Solorzano, H. Zeng, L.A. Perrone, P. Palese, A. Garcia-Sastre, J.M. Katz, and T.M. Tumpey | Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus | Proc. Natl. Acad. Sci. USA 105:3064-3069 | |
| Perrone, L.A., J.K. Plowden, A. Garcia-Sastre, J.M. Katz, and T.M. Tumpey | H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice | PLoS Pathog. 4:e1000115 | |
| Stevens, J., O. Blixt, L.M. Chen, R.O. Donis, J.C. Paulson, and I.A. Wilson | Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity | J. Mol. Biol. 381:1382-1394 | |
| Wei, C.J., L. Xu, W.P. Kong, W. Shi, K. Canis, J. Stevens, Z.Y. Yang, A. Dell, S.M. Haslam, I.A. Wilson, and G.J. Nabel | Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus | J. Virol. 82:6200-6208 | |
| Xu, X. Zhu, R.A. Dwek, J. Stevens, and I.A. Wilson | Structural characterization of the 1918 influenza H1N1 neuraminidase | J. Virol. 82:10493-10501 | |
| Yu, X., T. Tsibane, P.A. McGraw, F.S. House, C.J. Keefer, M.D. Hicar, T.M. Tumpey, C. Pappas, L.A. Perrone, O. Martinez, J. Stevens, I.A. Wilson, P.V. Aguilar, E.L. Atlschuler, C.F. Basler, and J.E. Crowe, Jr. | Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors | Nature 455:532-536 | |
| Zhu, X., X. Xu, and I.A. Wilson | Structure determination of the 1918 H1N1 neuraminidase from a crystal with lattice-translocation defects | Acta Crystallogr. D. Biol. Crystallogr. 64:843-850 | |
| 2007 TOP | Ahmed, R., M. B. A. Oldstone, and P. Palese | Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic | Nature Immunol. 8:1188-1193 |
| Baskin, C.R., H. Bielefeldt-Ohmann, A. Garcia-Sastre, T.M. Tumpey, N. Van Hoeven, V.S. Carter, M.J. Thomas, S. Proll, A. Solorzano, R. Billharz, J.L. Fornek, S. Thomas, C.H. Chen, E.A. Clark, M.K. Kaja, and M.G. Katze | Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus | J. Virol. 81:11817-11827 | Informatics Server |
| Basler, C.F. | Influenza viruses: basic biology and potential drug targets | Infect. Disord. Drug Targets 7:282-293 | |
| Conenello, G.M. and P. Palese | Influenza A virus PB1-F2: a small protein with a pig punch | Cell Host Microbe 2:207-209 | |
| Conenello, G. M., D. Zamarin, L. A. Perrone, T. Tumpey, and P. Palese | A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence | PLoS Pathog. 3:e141 | |
| Escalante, C.R., E. Nistal-Villan, L. Shen, A. Garcia-Sastre, and A.K. Aggarwal | Structure of IRF-3 bound to the PDRIII-I regulatory element of the human interferon-beta enhancer | Mol. Cell 26:703716 | |
| Fornek, J.L., M.J. Korth, and M.G. Katze | Use of functional genomics to understand influenza-host interactions | Adv. Virus Res. 70-81-100 | |
| Glaser, L., G. Conenello, J. Paulson, and P. Palese | Effective replication of human influenza viruses in mice lacking a major alpha 2,6 sialyltransferase | Virus Res. 126:9-18 | |
| Grimm, D., P. Staeheli, M. Hufbauer, I. Koerner, L. Martinez- Sobrido, A. Solorzano, A. Garcia-Sastre, O. Haller, and G. Kochs | Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene | Proc. Natl. Acad. Sci. USA 104:6806-6811 | |
| Kochs, G., A. Garcia-Sastre, and L. Martinez-Sobrido | Multiple anti-interferon actions of the influenza A virus NS1 protein | J. Virol. 81:7011-7021 | |
| Lenschow, D. J., C. Lai, N. Frias-Staheli, N. V. Giannakopoulos, A. Lutz, T. Wolff, A. Osiak, B. Levine, R. E. Schmidt, A. Garcia-Sastre, D. A. Leib, A. Pekosz, K.-P. Knobeloch, I. Horak, and H. W. Virgin IV | IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes and Sindbis viruses | Proc. Natl. Acad. Sci. USA 104:1371-1376 | |
| Taubenberger, J. K., J. Hultin, and D. Morens | Discovery and characterization of the 1918 pandemic influenza virus in historical context | Antiviral Therapy 12:581-591 | |
| Taubenberger, J. K., D. Morens, and A. S. Fauci | The next influenza pandemic: can it be predicted? | JAMA 297:2025-2027 | |
| Ten Oever, B. R., S.-L. Ng, M. A. Chua, S. M. McWhirter, A. Garcia-Sastre, and T. Maniatis | Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity | Science 315:1274-1278 | |
| Tumpey, T. M., T. R. Maines, N. van Hoeven, L. Glaser, A. Solorzano, C. Pappas, N. J. Cox, D. E. Swayne, P. Palese, J. M. Katz, and A. Garcia-Sastre | A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission | Science 315:655-659 | |
| Tumpey, T. M., K. J. Szretter, N. Van Hoeven, J. M. Katz, G. Kochs, O. Haller, A. Garcia-Sastre, and P. Staeheli | The Mx1 gene protects mice against the pandemic 1918 and highly lethal H5N1 influenza viruses | J. Virol. 81:10818-10821 | |
| 2006 TOP | |||
| Baas, T., C. R. Baskin, D. L. Diamond, A. Garcia-Sastre, H. Bielefeldt-Ohmann, T. M. Tumpey, M. J. Thomas, V. S. Carter, T. H. Teal, N. Van Hoeven, S. C. Proll, J. M. Jacobs, Z. R. Caldwell, M. A. Gritsenko, R. R. Hukkanen, D. G. Camp, R. D. Smith, and M. G. Katze | An integrated molecular signature of disease: analysis of influenza virus-infected macaques through functional genomics and proteomics | J. Virol. 80:10813-10828 | Informatics Server NCRR Proteomics |
| Garcia-Sastre, A. | Antiviral response in pandemic influenza viruses | Emerg. Infect. Dis. 12:44-47 | |
| Garcia-Sastre, A. and C. A. Biron | Type 1 interferons and the virus-host relationship: a lesson in detente | Science 312:879-882 | |
| Garcia-Sastre, A. and R. Whitley | Lessons learned from reconstructing the 1918 influenza virus pandemic | J. Infect. Dis. 94: S127-S132 | |
| Glaser, L., G. Conenello, J. Paulson, and P. Palese | Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice | J. Virol. 80:7976-7983 | |
| Kash, J. C., T. M. Tumpey, S. C. Proll, V. Carter, O. Perwitasari, M. J. Thomas, C. F. Basler, P. Palese, J. K. Taubenberger, A. Garcia-Sastre, D. E. Swayne, and M. G. Katze | Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus | Nature 443:578-581 | Informatics Server |
| Kong, W., P., C. Hood, Z. Y. Yang, C. J. Wei, L. Xu, A. Garcia-Sastre, T. M. Tumpey, and G. J. Nabel | Protective immunity to lethal challenge of the 1918 pandemic influenza virus by vaccination | Proc. Natl. Acad. Sci. USA 103:15987-15991 | |
| Palese, P. | Making better influenza virus vaccines? | J. Infect. Dis. 12:61-65 | |
| Palese, P., T. M. Tumpey, and A. Garcia-Sastre | What can we learn from reconstructing the extinct 1918 pandemic influenza virus? | Immunity 24:121-124 | |
| Stevens, J., O. Blixt, J. C. Paulson, and I. A. Wilson | Glycan microarray technologies: tools to survey host specificity of influenza viruses | Nature Rev. Microbiol. 4:857-864 | |
| Stevens, J., O. Blixt, T. M. Tumpey, J. K. Taubenberger, J. C. Paulson, and I. A. | Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus | Science 312:404-410, Wilson | |
| Taubenberger, J. K. | The origin and virulence of the 1918 "Spanish" influenza virus | Proc. Am. Philos. Soc. 150:86-112 | |
| Taubenberger, J. K. and D. Morens | 1918 Influenza: the mother of all pandemics | Emerg. Infect. Dis. 12:15-22 | |
| Taubenberger, J. K. and D. Morens | Influenza revisited | Emerg. Infect. Dis. 12:1-2 | |
| Zamarin, D., M.B. Ortigoza, and P. Palese | Influenza A virus PB1-F2 protein contributes to viral pathogenesis in mice | J. Virol. 80:7976-7983 | |
| 2005 TOP | |||
| Bourmakina, S. V. and A. Garcia-Sastre | The morphology and composition of influenza A virus particles are not affected by low levels of M1 and M2 proteins in infected cells | J. Virol. 79:7926-7932 | |
| Glaser, L, J. Stevens, D. Zamarin, I. A. Wilson, A. Garcia-Sastre, T. M. Tumpey, C. F. Basler, J. K. Taubenberger, and P. Palese | A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity | J. Virol. 79:11533:11546 | |
| Holmes, E.C., B.T. Grenfell, and J.K. Taubenberger | Heading off an influenza pandemic | Science 309:989 | |
| Shaw, M.L. and P. Palese | Viruses and the innate immune system | p. 1-18. In P. Palese (ed.) Modulation of host gene expression and innate immunity by viruses | |
| Taubenberger, J. K. | The virulence of the 1918 pandemic virus: unraveling the enigma | Arch. Virol. Suppl. 19:101-115 | |
| Taubenberger, J.K., A.H. Reid, and T.G. Fanning | Capturing a killer flu | Sci. Am. 292-48-57 | |
| Taubenberger, J. K., A.H. Reid, R.M. Lourens, R. Wang, G. Jin, and T.G. Fanning | Characterization of the 1918 influenza virus polymerase genes | Nature 437:889-893 | |
| Tumpey, T. M., C. F. Basler, P. V. Aguilar, H. Zeng, A. Solorzano, D. E. Swayne, N. J. Cox, J. M. Katz, J. K. Taubenberger, P. Palese, and A. Garcia-Sastre | Characterization of the reconstructed 1918 Spanish influenza pandemic virus | Science 310:77-80 | |
| Tumpey, T. M., A. Garcia-Sastre, J. K. Taubenberger, P. Palese, D. E. Swayne, M. J. Pantin-Jackwood, S. Schultz-Cherry, A. Solorzano, N. Van Rooijen, J. M. Katz, and C. F. Basler | Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice | J. Virol. 79:14933-14944 | |
| Zamarin, D. A. Garcia-Sastre, X. Xiao, R. Wang, and P. Palese | Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1 | PLoS Pathog. 1:e4 | |
| 2004 TOP | |||
| Baskin, C. R., A. Garcia-Sastre, T. M. Tumpey, H. Bielefeldt-Ohmann, V. S. Carter, E. Nistal-Villan, and M. G. Katze | Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina). | J. Virol. 78:10420-10432 | Informatics Server |
| Kash J.C., C.F. Basler, A. Garcia-Sastre, V. Carter, R. Billharz, D.E. Swayne, R.M. Przygodzki, J.K. Taubenberger, M.G. Katze, and T.M. Tumpey | Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus | J. Virol. 78:9499-9511 | Informatics Server |
| Palese, P. | Influenza: old and new threats | Nature Med. 10:S82-S87 | |
| Reid, A.H., T.G. Fanning, T.A. Janczewski, R.M. Lourens, and J.K. Taubenberger | Novel origin of the 1918 pandemic influenza virus nucleoprotein gene | J. Virol. 78:12462-12470 | |
| Reid, A.H. and J.K. Taubenberger | Evidence of an abscence: the genetic origins of the 1918 pandemic influenza virus | Nat. Rev. Microbiol. 2:909-914 | |
| Stevens J., A. L. Corper, C. F. Basler, J. K., Taubenberger, P. Palese, and I. A. Wilson | Structure of uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus | Science 303:1866-1870 | |
| Tumpey T. M., A. Garcia-Sastre, J. K., Taubenberger, P. Palese, D. E. Swayne, and C. F. Basler | Pathogenicity and immunogenicity of influenza viruses with genes from the 1918 pandemic virus | Proc. Natl. Acad. Sci. USA 101:3166-3171 | |